EndoStream develops aneurysm devices,
utilizing self-conforming scaffolds that adapt to an aneurysm’s unique shape
and provide maximal neck metal coverage
NautilusTM
Maximizing neck coverage and enhancing coil stability,
to optimize intrasaccular thrombosis and enable progressive occlusion
The Nautilus™ is not approved for sale or distribution in the US and is limited by U.S. law to investigational use.
Please read IFU before use and for additional info on indications, contraindications, warnings, and precautions.
The Nautilus Edge
Self-conforming structure
maximal metal coverage
& endothelial remodeling
No intraluminal components
A-traumatic deployment
Thin delivery profile
by using any .0165" microcatheter
Entire device is radiopaque
Self-conforming structure
maximal metal coverage
& endothelial remodeling
No intraluminal components
A-traumatic deployment
Thin delivery profile
by using any .0165" microcatheter
Entire device is radiopaque
About Us
EndoStream is dedicated to developing safe and effective solutions
that significantly improve clinical outcomes for patients suffering from brain aneurysms
Danel Mayer
Danel is the founder and CEO of EndoStream Medical. Before EndoStream, he founded Rapid Medical (now held by MicroPort), where he spent five years leading the company from inception to clinical trials. Prior to that he spent several years in the San Francisco Bay Area working as a product manager at Concentric Medical (acquired by Stryker) and as a business-development intern at Kerberos (acquired by ev3). Danel also previously worked as a lending associate for healthcare companies at the corporate finance division of Israel’s largest bank.
Danel holds an MBA from the Haas School of Business at UC Berkeley and a dual Bachelor’s from Tel Aviv University in Psychology and Economics.
Alon May
Alon is the founder and CTO of EndoStream Medical. He has vast experience in leading complex engineering projects in medical device startups, overseeing the clinical need definition, characterization, design, and validation. Prior to co-founding EndoStream he served in managerial roles at Superdimension (a multidisciplinary system for navigation in the lungs acquired by Covidien) and Executive roles as VP Engineering and Operations at EndoCross (a catheter-based system for treating coronary and peripheral CTO) and CEO at Intratech Medical (a thrombectomy catheter for ischemic stroke).
Alon holds a B.Sc. in Mechanical Engineering from Israel Institute of Technology and he is a Lieutenant commander (reserve) in the Israeli navy.
J Mocco, MD, MS
Dr. Mocco is a cerebrovascular and endovascular neurosurgeon with clinical interests in stroke, brain aneurysms, subarachnoid hemorrhage, arteriovenous malformations, cavernous malformations, carotid artery stenosis, intracranial stenosis, and brain tumors. He serves as a Professor and Senior System Vice Chair in the Department of Neurosurgery at Mount Sinai, as well as Director of the Cerebrovascular Center. Dr. Mocco was previously Associate Professor of Neurological Surgery, Radiology, and Radiological Sciences at Vanderbilt University Medical Center.
Dr. Mocco has published more than 525 peer-reviewed publications, edited three texbooks on neurosurgical techniques, and runs numerous national and international clinical trials to improve the treatment of patients with cerebrovascular disease.
Hadas Abalia
Hadas brings years of experience in conducting and managing clinical trials in various medical centers and healthcare companies. She has strong project management skills, leading projects & complex processes from idea to execution. Prior to joining EndoStream, Hadas served as a clinical project specialist at Syqe Medical and as a Clinical Research Manager at Rabin Medical Center.
Hadas holds an MBA from Bar-Ilan University and a B.sc. in Nutritional Science from Tel-Hai college.
Alejandro Berenstein, MD
Dr. Berenstein is one of the founding fathers of Interventional Neuroradiology. He is a Clinical Professor and Director of the Pediatric Cerebrovascular Program at the Mount Sinai Health System in New York City.
Dr. Berenstein contributed to over 180 peer-reviewed publications, more than 40 chapters in the field, and 9 books. He is the past President of the World Federation of Interventional and Therapeutic Neuroradiology (WFITN), the Society of NeuroInterventional Surgery (SNIS) and the Latin-American Society of Neuroradiology (SILAN).
Danel Mayer
Danel is the founder and CEO of EndoStream Medical. Before EndoStream, he founded Rapid Medical (now held by MicroPort), where he spent five years leading the company from inception to clinical trials. Prior to that he spent several years in the San Francisco Bay Area working as a product manager at Concentric Medical (acquired by Stryker) and as a business-development intern at Kerberos (acquired by ev3). Danel also previously worked as a lending associate for healthcare companies at the corporate finance division of Israel’s largest bank.
Danel holds an MBA from the Haas School of Business at UC Berkeley and a dual Bachelor’s from Tel Aviv University in Psychology and Economics.
Alon May
Alon is the founder and CTO of EndoStream Medical. He has vast experience in leading complex engineering projects in medical device startups, overseeing the clinical need definition, characterization, design, and validation. Prior to co-founding EndoStream he served in managerial roles at Superdimension (a multidisciplinary system for navigation in the lungs acquired by Covidien) and Executive roles as VP Engineering and Operations at EndoCross (a catheter-based system for treating coronary and peripheral CTO) and CEO at Intratech Medical (a thrombectomy catheter for ischemic stroke).
Alon holds a B.Sc. in Mechanical Engineering from Israel Institute of Technology and he is a Lieutenant commander (reserve) in the Israeli navy.
J Mocco, MD, MS
Dr. Mocco is a cerebrovascular and endovascular neurosurgeon with clinical interests in stroke, brain aneurysms, subarachnoid hemorrhage, arteriovenous malformations, cavernous malformations, carotid artery stenosis, intracranial stenosis, and brain tumors. He serves as a Professor and Senior System Vice Chair in the Department of Neurosurgery at Mount Sinai, as well as Director of the Cerebrovascular Center. Dr. Mocco was previously Associate Professor of Neurological Surgery, Radiology, and Radiological Sciences at Vanderbilt University Medical Center.
Dr. Mocco has published more than 525 peer-reviewed publications, edited three texbooks on neurosurgical techniques, and runs numerous national and international clinical trials to improve the treatment of patients with cerebrovascular disease.
Hadas Abalia
Hadas brings years of experience in conducting and managing clinical trials in various medical centers and healthcare companies. She has strong project management skills, leading projects & complex processes from idea to execution. Prior to joining EndoStream, Hadas served as a clinical project specialist at Syqe Medical and as a Clinical Research Manager at Rabin Medical Center.
Hadas holds an MBA from Bar-Ilan University and a B.sc. in Nutritional Science from Tel-Hai college.
Alejandro Berenstein, MD
Dr. Berenstein is one of the founding fathers of Interventional Neuroradiology. He is a Clinical Professor and Director of the Pediatric Cerebrovascular Program at the Mount Sinai Health System in New York City.
Dr. Berenstein contributed to over 180 peer-reviewed publications, more than 40 chapters in the field, and 9 books. He is the past President of the World Federation of Interventional and Therapeutic Neuroradiology (WFITN), the Society of NeuroInterventional Surgery (SNIS) and the Latin-American Society of Neuroradiology (SILAN).
See it in action
